Worldwide Patented Formula

Lyriana is based around a worldwide patented formula that combines vasoactive agents used for the treatment of female sexual dysfunction. Lyriana has been awarded the following worldwide patent for its unique effectiveness in this area.

Publication Number: WO/2005/004890
International Application No.: PCT/EP2004/007374
Publication Date: 20.01.2005
International Filing Date: 06.07.2004
Chapter 2 Demand Filed: 04.05.2005

Int. Class.: A61K 31/352 (2006.01)
Applicants: INDENA S.P.A. [IT/IT]; Viale Ortles, 12, I-20139 Milano (IT) (All Except US). BOMBARDELLI, Ezio [IT/IT]; Via Gabetta, 13, I-27027 Groppello Cairoli (IT) (US Only).
Inventor: BOMBARDELLI, Ezio [IT/IT]; Via Gabetta, 13, I-27027 Groppello Cairoli (IT).
Agent: BIANCHETTI, Giuseppe; Via Plinio, 63, I-20129 Milano (IT).
Priority Data: MI2003A001428 11.07.2003 IT

This invention relates to combinations of vasoactive substances which are useful in the treatment of sexual dysfunctions associated with poor local blood supply and/or insufficient lubrication. The active compounds are selected from a: - esculoside or visnadine; - forskolin or extracts containing it, or alternatively, purified lipophilic extracts of plants of the genus Ipomea; - esters of ximenynic acid; - optionally, at least one compound selected from a icarin or derivatives or extracts thereof which contain it, amentoflavone, and Gingko biloba dimeric flavones. The combination of these vasoactive substances is incorporated in gels and lotions designed to be applied to the genital organs. These formulations are useful in inducing erection of the male and female sex organs and enhancing orgasm and sexual performance. The formulations are particularly useful in the treatment of female sexual dysfunctions.

Designated States:
AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW. African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW) Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM) European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR) African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

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